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International Isotopes Inc. Announces the Filing of Domestic and International Patent Applications for the Company’s Fluorination Technology

Wednesday, June 04, 2008

Idaho Falls, ID -- International Isotopes Inc. (OTC Bulletin Board: INIS) is pleased to announce it has filed five domestic and international patent applications for its promising fluorination technology.

During 2007 and 2008, INIS’s Fluorine Products Division evaluated the feasibility of using germanium tetrafluoride and silicon tetrafluoride as fluorinating agents for the production of organo-fluorine products. In a series of small-scale experiments, it successfully demonstrated that both germanium tetrafluoride and silicon tetrafluoride could be used as fluorinating agents for the direct production of certain hydro fluorocarbons. The Company believes this technology could have beneficial applications for the production of certain pharmaceutical compounds, agro chemicals, and certain fluorinated olefins. INIS would like to stress this technology is in very early development and more research needs to be done to demonstrate true commercial applications.

Steve T. Laflin President and Chief Executive Officer of INIS stated, "We are very pleased with the initial early results from this promising fluorination technology and believe these experiments represent a significant advance in organo-fluorine chemistry. This technology potentially fits in very well with our announcement today of our planned large-scale uranium de-conversion and fluorine extraction facility. We expect that facility will produce large volumes of fluoride gases such as SiF4.

"Since the feedstock material for this fluorine gas production is a waste material, we believe our production costs will be competitive with current fluoride gas manufacturing processes. We plan to continue research into developing these fluorination technologies with an ultimate goal of expanding the markets for the high purity fluoride gases we produce using our patented Fluorine Extraction Process. Current uses for these high purity gases include microelectronics applications, fiber optic cable manufacturing, and production of photovoltaic films for various solar cell applications.

"I do want to stress these developments are at a very early stage but obviously, if successful, it would increase the markets for our fluoride gases."

About International Isotopes Inc.

International Isotopes Inc. manufactures a full range of nuclear medicine calibration and reference standards, high purity fluoride gases, and a variety of cobalt-60 products such as teletherapy sources. The Company also provides a wide selection of radioisotopes and radiochemicals for medical devices, calibration, clinical research, life sciences, and industrial applications and provides a host of analytical, measurement, recycling, and processing services on a contract basis to clients.

International Isotopes Inc. Safe Harbor Statement

Forward-looking statements in this press release are made pursuant to the safe harbor provision of the federal securities laws. Information contained in forward-looking statements is based on current expectations and is subject to change. Actual results may differ materially from the forward-looking statements. Many factors could cause actual results to differ materially from the forward-looking statements. Readers are directed to read the risk factors detailed from time to time in our filings with the Securities and Exchange Commission, including our annual report on Form 10-KSB for the year ending December 31, 2006. The Company does not intend to publicly release any revisions to these forward-looking statements to reflect events or circumstances after the date hereof or to reflect the occurrence of unanticipated events.

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