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Allon Receives Japanese Patent Allowance for Treatment and Prevention of Major Neurological Diseases
Wednesday, January 06, 2010
Vancouver, British Columbia -- Allon Therapeutics Inc. (TSX: NPC) announced today that it has been allowed a Japanese patent, covering its two neuroprotection technology platforms. This patent provides protection for the treatment and prevention of a large number of disorders involving learning and memory deficits, such as those in Alzheimer's disease, Down syndrome and normal aging.
The Japanese patent covers the combination use of various derivatives of compounds from Allon's activity-dependent neuroprotective protein (ADNP) and activity-dependent neurotrophic factor (ADNF) platforms.
About Allon's neuroprotective platforms
Allon's two neuroprotective technology platforms are based on two naturally occurring proteins produced by the brain in response to a range of insults. The platforms are activity-dependent neuroprotective protein (ADNP) and activity-dependent neurotrophic factor (ADNF).
Because the two platforms are based on different proteins, the drugs from each are unique molecules with different mechanisms of action and distinct commercial opportunities. The clinical-stage drug, davunetide is based on ADNP, and its therapeutic potential is focused on frontotemporal dementia, Alzheimer's disease, and cognitive impairment in schizophrenia. The preclinical stage drug candidate AL-309 is derived from ADNF and is being developed for the treatment of peripheral neuropathies.
Allon Therapeutics Inc. is a clinical-stage biotechnology company developing treatments for major neurodegenerative conditions. Allon's drug davunetide has demonstrated human efficacy in amnestic mild cognitive impairment, a precursor to Alzheimer's disease, and cognitive impairment associated with schizophrenia. Allon has advanced human clinical programs pursuing large markets of unmet medical need, such as Alzheimer's disease and cognitive impairment associated with schizophrenia, and in orphan markets, such as frontotemporal dementia. The Company is listed on the Toronto Stock Exchange under the trading symbol "NPC" (Neuro Protection Company) and based in Vancouver. For additional information please visit the Company's website: www.allontherapeutics.com.
Forward Looking Statements
Statements contained herein, other than those which are strictly statements of historical fact may include forward-looking information. Such statements will typically contain words such as "believes", "may", "plans", "will", "estimate", "continue", "anticipates", "intends", "expects", and similar expressions. While forward-looking statements represent management's outlook based on assumptions that management believes are reasonable, forward-looking statements by their nature are subject to known and unknown risks, uncertainties and other factors that may cause the actual results, events or developments to be materially different from any future results, events or developments expressed or implied by them. Such factors include, among others, the inherent uncertainty involved in scientific research and drug development, Allon's early stage of development, lack of product revenues, its additional capital requirements, the risks associated with successful completion of clinical trials and the long lead-times and high costs associated with obtaining regulatory approval to market any product which Allon may eventually develop. Other risk factors include the limited protections afforded by intellectual property rights, rapid technology and product obsolescence in a highly competitive environment and Allon's dependence on collaborative partners and contract research organizations. These factors can be reviewed in Allon's public filings at www.SEDAR.com and should be considered carefully. Readers are cautioned not to place undue reliance on such forward-looking statements and Allon disclaims any obligation to update or announce changes in any such factors except in its periodic filings.
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